Solve the Number Sequence: 0, +15, -16, ?0

Let's solve the exercise from left to right:

$\frac{0}{15}=$

Remember the formula:

$\frac{0}{x}=0$

If we divide zero by any number, the result will always be zero.

Now we are left with the following exercise:

$0:-16?0$

Let's solve the exercise:

$\frac{0}{-16}=$

If we remember the formula above, we should see that the result is zero.

The final exercise will look like this:

$0\text{?}0$

Therefore, the missing sign is:

$0=0$