Simplify Powers of 2: 2³ × 2⁴ × 2⁶ × 2⁵

To reduce the expression $2^3 \times 2^4 \times 2^6 \times 2^5$, we apply the rule of multiplication for exponents with the same base, which states that:

$a^m \times a^n = a^{m+n}$.

Following this rule, we add up all the exponents together since they all have the same base, 2:

$3 + 4 + 6 + 5 = 18$.

So, the expression reduces to $2^{18}$.

Thus, the answer is $2^{18}$.